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Dementia


Overview, Types, Incidence and Prevalence, Risk Factors

Physician developed and monitored.

Original source: www.neurologychannel.com
Original Date of Publication: 02 Jan 2000
Reviewed by: Stanley J. Swierzewski, III, M.D.

Home » Dementia » Overview, Types, Incidence and Prevalence, Risk Factors

Overview

Dementia refers to a loss of cognitive function (cognition) due to changes in the brain caused by disease or trauma. The changes may occur gradually or quickly; and how they occur may determine whether dementia is reversible or irreversible.



Cognition is the act or process of thinking, perceiving, and learning. Cognitive functions that may be affected by dementia include the following:

  • Decision making, judgment
  • Memory
  • Spatial orientation
  • Thinking, reasoning
  • Verbal communication

Dementia also may result in behavioral and personality changes, depending on the area(s) of the brain affected.

Types

Some dementia is reversible and can be cured partially or completely with treatment. The degree of reversibility often depends on how quickly the underlying cause is treated.



Irreversible dementia is caused by an incurable condition (e.g., Alzheimer's disease). Patients with irreversible dementia are eventually unable to care for themselves and may require round-the-clock care.

Incidence and Prevalence
An estimated 2 million people in the United States suffer from severe dementia and another 1 to 5 million people experience mild to moderate dementia. Five to eight percent of people over the age of 65 have some form of dementia and the number doubles every 5 years over age 65.

The prevalence of dementia has increased over the past few decades, either because of greater awareness and more accurate diagnosis, or because increased longevity is creating a larger population of elderly, which is the age group most commonly affected.

Risk Factors

The greatest risk factor for dementia is advanced age. Inheriting the genes associated with Alzheimer's or Huntington's disease is a risk factor. Untreated infectious and metabolic disease and substance abuse also can lead to dementia.

Other risk factors include the following:

  • Brain tumor
  • Cardiovascular disease (e.g., hypertension, atherosclerosis)
  • Head injury
  • Kidney failure, liver disease, thyroid disease
  • Vitamin deficiencies: B12, folic acid, B1 (thiamine)



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